Towards cardiopulmonary resuscitation without vasoactive drugs

Key points of sistematic analysis about ALS managent of Out of Hospital Cardiac Arrest (OHCA):

1. No evidence that any of the commonly used vasoactive drugs are beneficial on neurological outcome

2. Controversial evidences on antiarrhythmics drugs effectivness

3. Only good quality CPR and electric therapy improves outcome

4. Ultra Sonography for diagnosis of underliyng reversible causes and targeted therapies on individual patient’s response must be implemented

5. EtCO2, Near-infrared spectometry, VF analysis, Extracorporeal Membrane Oxygenation must be part of future management

And ROSC is not the finish line but only a step to it. More and more voices are rising toward the definition of an Early Goal Directed Post-Resuscitative Care!

References:

Towards cardiopulmonary resuscitation without vasoactive drugs

Image attribution:

Kjetil Sunde,Theresa M. Olasveengen

Tags: ALS drugs, ECMO, epinephrine, EtCO2, OHCA, Out of Hospital Cardiac Arrest, vasopressine